Sunday, January 30, 2022

"SOCIALIZED MEDICINE?"


                               Linda and friend, Isle of Skye

In the past few years I have become increasingly persuaded that the future of medical care here in the United States should include a single-payer system, much like those in the UK and Canada.  I used to regard this sort of thing as “socialized medicine”, sure to cost a lot, create a bureaucratic nightmare, and in general deliver poor value for money.  Now, I’m not so sure.  I predicted that Obamacare was a step in that direction, and would fail.  Well, it certainly has been no flaming panacea – but it does seem to have helped, somewhat.  Thus, it Washington chooses to impose a Canada-like system on us, I won’t scream too loudly. 

However, it is well to consider counter-arguments.  The news item shown below – which concerns ovarian cancer – while anecdotal, is a case in point.  Read about this poor woman’s dilemma, and then see if you can come up with some alternatives.

https://vancouversun.com/opinion/columnists/daphne-bramham-desperate-cancer-specialist-shortage-meant-long-delays-even-before-covid 

Saturday, January 29, 2022

MORE ON "THE PILL"


 Linda and her mom on our patio in Borrego Springs

I have written several times about the beneficial side effect of relying on birth control pills to prevent undesired pregnancy.  Here is statistical proof, courtesy of a massive study performed in the UK, that it really works.  OVCA deaths are down 17% in that country, over a five year period.  This apparently is much greater than the equivalent statistic for the rest of Western Europe (~7%).  Part of these declines is attributable to advances in treatment and early detection, which presumably are substantially equivalent all over Western Europe; the difference here is attributed to the greater use of oral contraception in the UK.  Differences in the use of hormone replacement also contribute.  Statistics for the U.S* are more in line with continental Europe than with the UK.  The practical message then seems to be:  pill, good; hormones, bad.

And so, all you parents with young, unmarried daughters – if you find birth control pills in her purse, she may have a legitimate prophylactic excuse.  Or not.    (That was an attempt at humor which probably fell flat.  Sorry.)

https://www.theguardian.com/society/2022/jan/26/uk-ovarian-cancer-death-rate-down-17-since-2017-study-suggests 

*I dug this fact out using the SEER statistical system, which I have written about several times previously.  It wasn’t easy.  In an heroic effort to be inclusive and digitally sophisticated the SEER people also have done - in my opinion - a very fine job of gumming up the works!.

Sunday, January 23, 2022

GENETIC COUNCELLING


                                           Linda and my Mom

                                                          Probably 1984

This article discusses the importance of genetic counseling.  Under all but the most straightforward circumstances genetic counseling is useful, and some cases it is indispensable.  However, there aren’t enough genetic counselors to go around.  We need to produce more.  If you like biology, can tolerate math, and want to help people, consider the field.

My youngest daughter, Kristen, trained as a genetics counselor, and she would have been a good one.  However, several unfortunate tricks of fate forced her to abandon the field.  She still informs me when my ideas are cockeyed, so I guess her education wasn’t wasted.  Thanks for your help, Kristen.

https://www.onclive.com/view/genetic-counseling-for-ovarian-cancer

Tuesday, January 18, 2022

A NEW WEAPON AGAINST OVARIAN CANCER


 Part of the reason sold the cabin near Winthrop

Downright incredible! 

Researchers  at U. Arizona have devised something they call a falloposcope – a device only 0.8 mm in diameter that can be inserted into a woman’s fallopian tubes to detect the beginnings of cancer,  As you know, many – maybe most – ovarian cancers arise in the fallopian tubes, so this little gadget could prove to be an important weapon against OVCA.  Testing still is underway, but preliminary signs are encouraging.

I continue to be amazed at the skill and dedication of the onco-research community.   God bless ‘em!

https://news.arizona.edu/story/researchers-pilot-itty-bitty-device-earlier-ovarian-cancer-detection 

Sunday, January 16, 2022

CHRIS EVERETT AND OVCA


           On Sabbatical Leave at Northwestern

                           Probably 1985

 I doubt if any of you are unaware that Chris Everett, the famous superstar tennis whiz, has been diagnosed with ovarian cancer.  It hasbeen all over the news.   Most women (80% or more) who get such a diagnosis find themselves in Stage 3 or 4, and face an uphill battle to live five more years.  (Linda was Stage 3C, and lived for 3 ½ years.)  This dismal state of affairs arises because OVCA spreads rapidly, is tenacious when once established, and is very hard to detect while in an early stage.

Chris Everett’s diagnosis came about because of a “prophylactic hysterectomy” she voluntarily underwent because her sister had died of OVCA, and a defective BRCA gene was known to exist in the family.  As a result of having detected her cancer at such an early stage (1C), Everett has at least a 90% chance of living to a ripe old age.

There is a moral to this story.  If you have a near relative who suffered from OVCA, for God’s sake get tested for harmful genetic mutations.  Government should provide this service free – but, of course, it doesn’t; write your Congresspersons and complain.  And get tested at your own expense if OVCA is known to exist in your family.

Thursday, January 13, 2022

MORE ON A SECOND SURGERY


                                  Linda in a skinny phase

                                 Probably about 1985

                                               Cougar Divide

Here is more on recent trials to determine whether a second operation after relapse from ovarian cancer is warranted.  Turns out it may be – under fairly tightly constrained circumstances.  Three studies are discussed: one from the United States which found a second surgery ineffective, one from China which found it useful – and, finally a study from Europe showing it to be effective (in prolonging life) if the situation is right.  I guess the main lessons here are: (1) don’t have absolute faith in what the folks in white coats say, and (2) be sure to get treated by real experts in the field. 

I find this bit of news destressing, but we will of course muddle on..   

https://www.cancer.gov/news-events/cancer-currents-blog/2022/ovarian-cancer-return-surgery-desktop-iii?cid=eb_govdel 

Sunday, January 9, 2022

WAYS TO GIVE


 Linda and Viv Hailwood on a long hike in the Yorkshire Dales.

It seems to be a very slack season for significant news about ovarian cancer research; all the articles I find that seem appropriate for this blog already been explored, glowing tumors, for instance https://ljb-quiltcutie.blogspot.com/2021/11/tumors-that-glow-in-dark.html 

So I find I must resort to reminding you of worthy places to support.  You can go to the American Cancer Society, of course, but it funds work concerning all kinds of cancer and, moreover, as a vast enterprise must have considerable operating expenses.  The Ovarian Cancer Research Alliance (OCRA; https://ocrahope.org/) also must be expensive to operate, but has the virtue of being focused on ovarian cancer.  Perhaps a better choice would be the Marsha Rivkin Center for Ovarian Cancer Research (https://www.google.com/search?q=rivkin+center&oq=&aqs=chrome.0.69i59i450l8.425541680j0j15&sourceid=chrome&ie=UTF-8) , a smaller, even more tightly focused organization founded in honor of his wife by my number-one hero, retired Swedish oncologist Dr. Saul Rivkin.

But, as you knew I would, I most strongly recommend going straight to the horse’s mouth, so to speak, and give directly to the ovarian research programs at Fred Hutch, using the web page honoring my wife, Linda Joyce Beck: (https://secure.fredhutch.org/site/TR/PersonalFundraisingPages/General?px=1148821&pg=personal&fr_id=1573).   

We have raised nearly $30,000 through this source, which is not much as these things go – but way better than nothing.  I like to think that, for every dollar I donate a woman in, say 2040, will be spared a battle with OVCA.  Stupid, I know, but it makes me feel better!

 

 

 

 

Thursday, January 6, 2022

DR FRANCIS COLLINS RETIRES


 Dr. Francis Collins and our old friend, the corona virus

Horrible news!  My runner up for OVCA-battling hero of recent decades, Dr. Francis Collins, has retired.  Dr. Collins, as you all know, has been Director of NIH for a long time.  Before that, of course, he headed the “official” effort to decipher the human genome.  As NIH Director he directed the NIH thrust to apply genomics to the search for cures for many human diseases, especially cancer.  That, for instance, we know that mutations in the BRCA genes can vastly increase a woman’s chance of getting breast and ovarian cancer largely is the result of research overseen by Dr. Collins.

Collins also wrote blogs that I avidly awaited, studied, and reported on.  They were always clearly written, easy for a non-biologist to understand, interesting, and cast light on important doings in the medical world.  Possibly the new director (not yet chosen) will continue the blog tradition.  I hope so, but I doubt they will be up to the Collins standard.

Dr. Collins also wrote several books, one of which (The Language of Life) describes the decipherment of the genetic code.  He also published innumerable professional papers.  As you might guess, over the years he received many honors, including membership in the National Academy of Sciences.  He clearly deserves them.

It might surprise you to learn that Dr. Collins also is a practicing Christian.  Apparently like so many young scientists he began adult life as a confirmed atheist.  His conversion began, as related in his book The Language of God, with an encounter with another pro-faith book, Mere Christianity, written by the famous scholar/author C. S. Lewis.  I have read both books several times and seriously pondered their message, but remain unconvinced.  I still am "agnostic", in the true sense of the word.  Perhaps I simply don’t want to admit the existence of a god that would take away my Linda in such a cruel and wanton manner.  Being an ordinary human and not a Collins or Lewis, I can’t surmount that barrier.

Tuesday, January 4, 2022

DRINK TEA, LIVE LONGER


                                             Linda on Santorini

                                                    On a very hot day

Ii seems to be a very slow time period for news of ovarian cancer research.  I guess that could be a good thing, because it might mean that so much progress has been made already that the medical community has reached a “digestion” stage, of necessity entailing publication of strongly technical articles too abstruse for you and me.  Of course, it also might mean that the fight against OVCA has stalled.  Let’s hope not.

But, anyway, I did run on an article that will be of interest to all you folks who look to diet as a health tool.  If this study is correct, then drinking tea (real tea, not herbal imitations) will prolong longevity.  How?  Not sure, but probably has something to do with smothering inflammation.  Maybe that’s why my mother kept me on a diet of tea and dry toast whenever I was sick.

Here is the research, if you can call it that.

https://www.livestrong.com/article/13769531-tea-benefits-for-longevity/ 

Sunday, January 2, 2022

A LOOK BACKWARD


 Linda and an inveterate opponent of vaccination

                On the island of Santorini, many years ago

You may find these two web sites useful.  The first is a list of top OVCA-research reports, many of which may be familiar to you if you slavishly follow this blog.  The second describes some important new findings about how OVCA develops in women who are BRCA-1 positive.  The fallopian tubes are implicated, but you already knew that.  All the more reason to make genetic testing obligatory (and free) for every girl baby that makes her appearance on this rather sorrowful  planet.

Anyway, Happy New Year & stay healthy

https://www.healio.com/news/womens-health-ob-gyn/20211227/2021s-top-stories-about-breast-cervical-and-ovarian-cancer-research 

https://www.usnews.com/news/health-news/articles/2021-12-29/new-clues-to-how-ovarian-cancer-begins-and-might-be-prevented