HAPPY TIMES

It is funny where you can pick up OVCA news if you keep tuned. As many of you know, I often amuse myself by pretending to be Warren Buffett – “playing” the stock market, using my kids’ inheritance. So far, Warren is beating me pretty badly. However, from time to time I run on financial press releases that bear on OVCA research. I did so today. There is this little drug company-that-could, named Immunogen (formerly known as Celsion), located in Lawrenceville, NJ, that seems to have hit the jackpot. It has won fast-track approval from the FDA for one of its products (they call it EAHERE) that seems to be successful in the usual preliminary trials. EAHERE is an ADG, which stands for antibody drug conjugate. It is a means to deliver a lethal dose of toxicity directly to the cancer cells, that causes no harm elsewhere. In my primitive understanding, the process involves extracting T cells that are fighting cancer, cloning them by the billions in the lab, attaching them to a “messenger” molecule, then reinjecting the whole mess, now known as an antigen drug conjugate – ADC – into the patient. Sounds simple, huh? Not likely. But let’s hope. I am, however, not planning to plunk down real money on IMGN stock, I did that several years ago, when CELSION issued an optimistic press release. I doubt if Warren did. So far my loss hovers at 90%

LINDA AT 16

tHERE WILL BE LITTLE NEW HERE, BUT IT IS WELLEXPRESSED AND WORTH A GLANCE

PINEDALE, WYOMING

News about early detection, from a peculiar source/

INSIDE THE CRATER, SANTORINI

This is more of continuing experiment, designed to unfix the “upgrade” Bill Gates foisted on me several weeks ago. I now can get picture and text together but the web address gets plastered on the text part, making it hard to open. So, now I will try simply placing the computer stuff in a Comment. That way, those of you who are into the biology/medical stuff can get at it easily – and those of you who just like the pictures don’t have to feel guilty. Anyway, here goes.

HORNEY LADY

Genuine OVCA “news” has been scarce of late – unless of course, you have at least a MS in microbiology and are not intimidated by technical terms longer than the typical place name in rural Iceland. So, largely to test my new posting technique, I present below a news item from Fred Hutch, laying out their choice of the best Seattle docs for various maladies. I guess it might prove useful someday. Who knows? https://www.fredhutch.org/en/news/releases/2022/09/seattle-cancer-care-alliance-physicians-named-in-seattle-met-s-2.html

LINDA IN YORKSURE

I can think of almost no reasons to live in Los Angeles. One exception is the presence there of Cedars-Sinai Caner Institute, one of the very best in the world. They have recently published the results of some research, summarized below, done in conjunction with Cambridge University. The work involved the influence of “copy variations” on ovarian cancer susceptibility. Copy variations occur when dividing cells misplace or miscount a segment of DNA. The segment may be duplicated, misplaced, or eliminated altogether. If that “segment” is a gene associated with cancer prevention, such as BRCA, bad things may occur, It isn’t clear to me how this bit of knowledge will help eliminate OVCA – but, then, I’m just a dumb geologist. Anyway, read the article; it’s interesting. https://www.news-medical.net/news/20221011/Two-new-studies-help-improve-the-understanding-of-ovarian-cancer.aspx

TEMPLE FOR RAMSES II CHIEF WIFE

Here is some information I hope you will never need. It emanates from MD Anderson, one of the very top cancer clinics in the world. It is deficient in that it doesn’t explain how the cancer is further divided into sub-stages A, B, and C. I will leave that to you. https://www.mdanderson.org/cancerwise/ovarian-cancer-stages--how-they-are-determined.h00-159543690.html