Such a nice smile
“Autophagy” means “self-eating”, and the various autophagous processes are akin to urban garbage-disposal systems; they identify, transport and dispose of unwanted, sometimes dangerous, cellular elements. In macroautophagy, for instance, the damaged stuff is enclosed in a double membrane, then hauled off to an organelle known as a lysosome, where it is degraded and recycled. Without autophagy our cells would soon come to resemble my garage; so stuffed with junk as to be essentially non-functional.
There seem to be diseases that stem from haywire autophagy, and there are drugs that combat these diseases. Playing, it seems, on a hunch, people at U.C. San Diego have shown that these same drugs are effective against OVCA – at least in rats. More trials are in progress.
Make it so!