Saturday, October 24, 2015

IN-VITRO FERTILIZATION AND OVARIAN CANCER

Linda in Borrego Springs
No, wait.  This must be England
As most of you know, I use “Google Alerts” to help me keep up with developments in the ovarian cancer field.  Google Alerts isn’t very selective; it will feature a lurid apocalyptic article in a British tabloid  sandwiched between news from sources that are so sober and serious as to be the next best thing to an academic journal.  Of course, I ignore the splashy stuff (and puzzle over the rest).  Well, between October 20 and 23 there occurred a flurry of articles concerning a correlation between IVF (in vitro fertilization) and the probability of contracting ovarian cancer.  In a substantial British study, women who underwent IVF were about one third more likely to contract OVCA than women who did not.  The researchers hasten to say that the fault lies not with the IVF procedure itself, but rather the need for it.  In other words, some molecular mistake contributes both to infertility and ovarian-cancer susceptibility.  They are now searching for the causative link.  Good, fundamental biology, I guess.  Nine articles on this same subject were noted in three days.  Here is the most informative:
http://www.foodworldnews.com/articles/45755/20151021/can-infertility-point-to-ovarian-cancer-risk.htm
It should be pointed out that several of these articles note that this (British) result contradicts the findings of a much larger study performed recently in Sweden,  I consider this kind of thing  major drag.
And, if you have begun to think that cancer researchers all are meticulous, cautious and not given to premature enthusiasm, read this:
http://www.eurekalert.org/pub_releases/2015-10/uosc-boc101915.php
It appears that there is evidence that having a BRCA1 mutation enhances the ability to smell, in addition to increasing the probability of contracting breast and/or ovarian cancer.  This is the conclusion of a murine experiment.  (Murine means mouse.)  The statistics can’t be too griping, however: the whole damned thing had an N of 4!


1 comment:

  1. Now here is evidence that at least some people suspect that the IVF procedure itself may be to blame. Sounds fishy to me.

    http://www.ifreepress.com/4821-ivf-shock-study-treatment-could-increase-risk-of-cancer-by-a-third/

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