Sunday, January 25, 2015

A DEFINITE BUMMER

Linda and Ella, not so many years ago.
She was never happier than with a baby.
 
CBC radio broadcasts something called “White Coats, Black Arts”, which I’ve never heard.  Apparently this program dissects various aspects of medical science, successes and failures, leaving  warts and wrinkles in full view.  To me, this approach sounds like a welcome change  from the way it often is done on U.S. television – you know, Dr. Nancy Snyderman perched across the table from Brian, solemnly telling us something we already knew, or strongly suspected.  This strikes me as definitely better.  Yes, CBC is Canadian.  Face it, the Canucks are ahead of us, again.
The star of the show seems to be a Dr. Brian Goldman.  Dr. Goldman trained as an ER doc, has written a book on that subject, and apparently is a popular fixture on Canadian media.  In this article he takes on the efficacy of cancer screening.  He lobs us an 80 lb. medicine ball – a real downer.  Here it is:
In this article he reports on a new study published in the International Journal of Epidemiology and authored by some people at Stanford - which concludes that, in general, currently available cancer screening methods simply  don’t work.   (It should come as little surprise that one of the authors is our old friend John Ioannidis  – see, for instance:  http://ljb-quiltcutie.blogspot.com/2014/04/metrics-scourge-of-sloppy-science.html, and several other articles mentioned therein.)
To write the blunt truth, after my experience of the last few years I don’t find this surprising. 
Ioannidis and his crew define “work” as improving the chances of not dying.  Some tests do help, but most don’t.  Here is a paragraph that summarizes the problem:
There are several possible reasons why these screening tests have performed so poorly..  The screening test may not detect the cancer early enough to save a life.  It may be that no matter how early the cancer is detected, there is no good early treatment that cures the cancer.  In some cases, there is a treatment but the risks of the treatment are so great that they cancel out the benefits of early cancer detection.  Or, early detection leads to treatment that cures the cancer but the patient is more likely to die of other causes not related to the cancer.”  Tell me this isn’t a bummer!
However, Dr. Goldman’s piece does include some silver lining for this particular dark cloud.  Several new prognostic processes are mentioned, including one currently being tested on ovarian cancer that involves looking for the presence of a certain abnormal protein in the blood.  It also might be useful for other cancers, including breast cancer.  Let us hope! 
There’s more good stuff in this short article; I recommend that you all read it.  And, when I get back to Bellingham, near the Canadian border, I’m going to see if I can tune in on White Coats, Black Arts.  Not much hope, here in Borrego Springs.
 
 
B


1 comment:

  1. You can go to the iTunes store and subscribe to the podcast. There are lots of old ones to listen to. (Free.)

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