MISSMATCH REPAIR

Linda with yet another baby I am still struggling with this new Windows operating system (which was foisted on me, all unknowing, in the dead of night several weeks ago) in an effort to create well organized, attractive and readable blog postings. So there is nothing much of useful information here. Sorry. But: you know about the harmful effects of mutations of the BRCA genes. Turns out there is another mutation they look for: MMR. This stands for mismatch repair. When a cell divides, as you have known for years, the two strands of the DNA double helix separate and are copied to form the code for the new cells. As there are literally billions of bases to copy, inevitably some mistakes occur; MMR searches them out and repairs them. If the MMR gene is buggered, unrepaired mutations will accumulate – and some combination of them may lead to cancer. Google MMR and see if you can understand what comes forth. Now to see if I can post this properly.