Saturday, December 19, 2020

STILL MORE ON PARPi


         PICKING OUT GOURDS TO DECORATE

We have considered PARP inhibitors (PARPi) several times.  There are three currently approved for treatment of ovarian cancer:  drug names Lynparza, Zejula, Rubraca.  They are not a cure but rather a means to prolong PFS (progression-free survival) without recourse to more chemotherapy, which may seriously impact quality of life.  PARPi works best in cases where the BRCA gene is mutated, but may be of some benefit for other OVCA patients.  This article contains much useful information which, with luck, you will never need.  Read it anyway.

https://www.onclive.com/view/weighing-risks-and-benefits-is-critical-with-second-line-maintenance-parp-inhibition-in-ovarian-cancer

Note that it would be very beneficial to know one’s BRCA status.  Any blanket health care system that we may eventually adopt ought to cover BRCA testing for every female.  Tell your favorite local legislator. 

 

 


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