Wednesday, June 5, 2019

A DIGRESSION: Autism


Our skinny period
Probably early 80s
Cat is Whiskers

The latest Economist has a very interesting medical article that – while it doesn’t have an obvious connection to ovarian cancer – I would like to pass on to you.


Autism is often in the news, so you know what it is.  Now doctors talk about “ASD”, which stands for autism spectral disorder.  Asperger’s syndrome is on the ASD spectrum.  One in 59 newborns currently express some form of ASD.

Well, it turns out that ASD likely results from an abnormality in gut bacteria, and may respond to something called MTT (microbiota transfer therapy), involving – among other things – that favorite of 11-year-old boys, fecal transplants.  (See ancient blog https://ljb-quiltcutie.blogspot.com/2012/11/microbes-maketh-man.html  for context.)

 It appears that certain gut bacteria are necessary to the proper functioning of several neuro-transmitters that play a vital role in the brain.  Detailed and convincing cause-and-effect is absent, but it is robustly demonstrated that people with ASD consistently lack  specific bacterial species common to the human to the alimentary tract. 

This (recognition of the vital role of gut bacteria in human health) is described by some as a “paradigm shift” (think: plate tectonics or the atomic theory).  The research described by the Economist has been fast-tracked by the FDA, and is being avidly pursued by an outfit called Fox Therapeutic Group, located in Massachusetts.  If Fox were on the stock exchange and I had any money I would buy some of their stock.  But they aren’t. and I don’t.


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