Saturday, September 17, 2022
LINDA AND LAYRA HANSEN
You know how it works, DNA carries the code for what we are; proteins follow that code to do the work. However, there are intermediate steps. Something pries the DNA double helix apart, enabling genes to be “read” and converted into a molecule called mRNA, where the m stands for “messenger”, and the RMA part consists of a single-stranded molecule much like DNA. The purpose of mRNA is to transport the DNA code to a complicated bio-object called a ribosome, where it is “read” and converted into a protein.
But, of course, you knew all that.
Anyway, if your DNA is carrying something undesirable, you can attempt to halt the process by (1) correcting the malfunctioning gene, (2) somehow destroying the protein at birth, or (3) waylaying the pernicious mRNA object on its way to the ribosome. (2) is the usual practice; (1) is the goal of much investigation, while (3) as many of you know is the basis of many of our attempts to disarm the Covid virus.
So, anyway, some smart people in Oregon are working on a way to use mRNA therapy to combat OVCA and a bunch of related diseases. Their mouse-models are encouraging. Read all about it below. It’s relatively easy going.
https://www.sciencedaily.com/releases/2022/09/220913140855.htm
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