I still can't figure out where this is.
Any suggestions?
The Fred
Hutch Newsletter is out. It contains a
half-dozen interesting articles, ranging from Immunotherapy to Circadian
Rhythms. You could do worse than to
spend a few minutes reading it. Here it
is:
I
particularly appreciated the piece on ovarian cancer, partly because I know, or
at least have met, almost everyone mentioned.
I even have blogged about one of
them:
Much of this
article is about a “two-minute” questionnaire designed to determine whether or
not one is suffering from OVCA. It is
the product of work by Dr. Robyn Andersen, a clinical psychologist. Back in the day I proof-read several of Robyn’s
papers. Her questionnaire is given in
the article. Make sure your primary care
doc knows about it. Don't apply it to yourself and then obsess about it, though.
Another
interesting (to me, at least) article examines some of the mysterious nuts and
bolts of CAR-T immunotherapy. I learned
that in making the T-cell a “chimera” they festoon it with molecules that are
stuck in and penetrate the cell wall.
The outer end of these things is the “antigen receptor”; it recognizes,
and gloms onto, the cancer cell. When
this happens, the inner end activates “pathways” that turn the T-cell into a
lethal weapon. How all this happens, or
how they even know it happens is not explained.
Just as well.
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