Our skinny period
Would you have guessed that the U.C. San Diego School of
Medicine employs someone described as a “Data Scientist?” Well, read this article and you will see why.
Faithful Readers, and there are thousands, already know all
about precision medicine – that is, the creation of drugs or drug
combinations that target specific mutations.
They also know that before a drug can be marketed it must receive the
blessing of the FDA. The FDA also weighs
in on whether a drug approved for, say, colorectal cancer can be used to
combat, say, melanoma. Evidence that
such a drug allocation might be useful rests consists of evidence that the misbehaving
biological pathways in both cancer types stem from the same mutation(s).
Well, ye gods! There
are hundreds of cancer types involving thousands of mutations. Moreover there are so many drugs, extant and
conceivable, that only God (and the FDA, of course) can keep track of
them. Ergo: a Data Scientist is required. No doubt she drives a Porsche.
This article shows how one goes about determining which
drugs will work on which cancers. The
work to date mainly involves yeast; our furry murine friends are
threatened. There is so much work to do
that the UCSD people are attempting to farm it out internationally. ISIS need not apply.
For the mathematically-minded:
ReplyDeletehttp://www.spectroscopynow.com/details/ezine/1567a28b980/Multidimensional-algorithm-Cancer-detector.html?tzcheck=1