Saturday, August 27, 2022

TEAL TIME

She loved little things

It’s that time again – September is Ovarian Cancer Awareness Month.  Time to put on your teal cap and reach for your wallet.  This link tells you what more you might consider doing.

https://ocrfa.activehosted.com/index.php?action=social&chash=e53a0a2978c28872a4505bdb51db06dc.1343&s=aef543f8c49e6da908b51f0ba32d7ca4 

  


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Sunday, August 21, 2022

OF DOGS AND NANOYUBES


 Linda and Ella
Twelve years ago

 

We have known for some timethat dogs can detect ovarian cancer with their acute sense of smell.  Well, to be safe I ought to say that some dgs can detect OVCA sometimes.  Well, it now appears that we humans can do it, too – with an expensive tool called a nanotube, developed and tested at Sloan Kettering.  Presumably it is more sensitive than a dog, or else they wouldn’t be bragging about it.  So, good for them.  But, you can’t pet a nanotube!

https://www.drugdiscoverynews.com/a-molecular-nose-sniffs-out-ovarian-cancer-15462 

Monday, August 8, 2022

MORE ON ASPIRIN AND OVCA


 Linda in Athens

We have discussed this before.  A recent meta-analysis confirms that continued use of low-dose aspirin significantly reduces the risk of contracting OVCA,  (A meta-analysis is a fancy way of combining the results of many individual studies.)  Negative factors include increase in risk of internal bleeding, and (new to me) stroke.  So, I guess, you just pays your money and takes your chance, as they used to say back in Beaumont in the 1950s.  Also new to me was that non-steroidal anti-inflammatories such as Tylenol actually INCREASE the risk of OVCA.  As they also said in Beaumont, sometimes you can’t win for losen.   

https://ascopost.com/news/july-2022/meta-analysis-examines-link-between-aspirin-use-and-ovarian-cancer-risk/ 

Sunday, July 24, 2022

AN IMPROVED BIO-MARKER?


 The Joyce family
Quite som time ago

Nothing very earth shaking in the anti-OVCA line has crossed my computer lately, but I guess this is worth reporting.  As you surely know, a large part of the reason OVCA is so deadly is that it is very difficult to detect until it reaches an advanced stage.  Thus, much effort is expended in trying to develop sensitive bio-marker routines.  That is what my Fred Hutch research group worked on back then.  This article presents an advance on that front, utilizing a marker protein (HE4) discovered, if I remember correctly, by my Hutch research group.  Catch it early, improve longevity.  Not world class news, but welcome nonetheless.

https://www.aacc.org/cln/articles/2022/julyaugust/new-blood-biomarker-could-aid-ovarian-cancer-diagnosis 

Sunday, July 17, 2022

GOOD HEWS, CHAPTER 3


Two precious creatures 

This is another take on the research, out of Rice University, that had me so excited a few weeks ago.  There is little new here, but it is pleasing to read this good news again.  To capsulize:  It seems to be possible to implant miniscule globules of something that spews out doses of a potent cancer-killer, Il-2.  This not only offs the tumor, it teaches the immune system what to look for (and kill), thereby fighting metastases as well.  This procedure worked perfectly in mice.  I presume studies involving humans are in the offing.

I must not let my hopes climb too high; there are many possible slips lurking out there.  But, Geez!

https://www.wndu.com/2022/06/23/medical-moment-an-implantable-treatment-ovarian-cancer/ 


Sunday, July 3, 2022

ONE SMALL STEP FORWARD?


 Linda, Murphy, and Whiskers

I wrote earlier of Celsion, the little drug company that could, and its efforts to use genetics to combat ovarian cancer.  This article announces some encouraging results, and hints at FDA approval.  Be sure to notice that this trial was small – and that Celsion is desperate to raise its stock valuation.  I bought a few shares a year or so ago, and so far have lost over 60% of my initial investment! 

In an aside, I am glad I don’t have to separate cancer victims into a control group and a group that actually gets the stuff.  Thank God for computers and random-number generators!

https://www.curetoday.com/view/gene-therapy-gen-1-shows-promise-in-treating-advanced-ovarian-cancer